Demand for biopharmaceuticals is strong: biopharmaceutical active ingredients – in other words, genetically engineered drugs – accounted for seven of the ten top-selling medications in the world in 2018. And the proportion is set to rise, as biopharmaceuticals can be used to combat conditions such as multiple sclerosis and anaemia, as well as many forms of cancer and rare diseases, which cannot be treated with chemical and synthetic agents. But such efficacy comes at a price. While chemically produced medicines are “small molecules” that are relatively easy to manufacture and are available in tablet form, biopharmaceutical drugs usually comprise hundreds or thousands of atoms.
Switch to the News+Stories article about the ComBioPro project to learn more about how computer-based simulations enhance process knowledge which could significantly speed up the scale-up from the lab to production scale.